Aim: To 
examined Large and small scale yoghurts for presence of microorganisms of 
sanitary importance. Materials and Methods: A total of 100 random samples 
from various dairy shops, street vendors and supermarkets located in Qena city 
were collected within 2008 - 2010. 
 Results: The recorded results show 
that (92%) and (70%) of the examined small and large scale yoghurt samples had 
Psychrotrophic count with an average of 3.9 x 104 and 6.8 x103 respectively. It 
was found that Enterococci were detected in (58%) and (40%) with an average 
count of 1.72 x104 and 2.0 x 103 for the examined small and large scale yoghourt 
samples. S. aureus were detected in (72%) and (36%) with an average of 8.5 x 103 
and 9.41 x102 for both small and large scale yoghurt samples. Regarding yeast 
and moulds they were found in (94%) and (40%) with an average counts of 1.4 x 
104 for small scale and 3.9 x 102 of large scale yoghurt samples. Most probable 
number (MPN) technique showed that [(38), (20)], [(35), (17)] and [(30), (6)] 
out of the total examined small and large scale yoghurt samples were 
contaminated with coliform, Fecal coliform and E. coli respectively. The 
incidence of E. coli biotype I and II for examined small scale yoghurt samples 
were (63.4%) and (36.6%), while for the examined large scale yoghurt samples 
were (16.7) and (83.3) respectively. 
 Conclusions: Yoghurt samples 
obtained from Qena city markets constitute a high risk hazard to consumers. So 
suggestive hygienic measures to safeguard the consumer health. As well as, the 
recommended sanitary practices for improving quality of small and large scale 
yoghurt must be applied. Keywords: Enterococci, large and small scale 
yoghurt, Psychrotrophs, Staphylococcus aureus